I have considered trying ayahuasca but I'm too scared to do it. People say it's a good experience.
Ayahuasca is so powerful it might be better to start smoking Changa/DMT first and take some Weed/LSD (VERY SMALL DOSAGES). Then you get a feeling of what it is about to overcome fears.
I personally do not mix these substances anymore but I did it in the past. Whatever you do be respectful to your health, have good intentions and take responsibility for your decision.