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Sk8eM dUb
replied 2292d
You assume that DNA is useful without a cell and that it's durable in an aerobic environment. Analogous to saying that if there's a library full of books a reader will magically appear
replied 2292d
not necessarily, Highly Efficient Self-Replicating RNA Enzymes https://www.cell.com/action/showPdf?pii=S1074-5521%2813%2900426-2
Sk8eM dUb
replied 2292d
What?? So this thing is going to build a cell around itself? All the plans in the world mean nothing if you don't have a factory to produce them in the first place.
replied 2291d
You asked for proof of heritable code that is “useful without a cell and that it's durable in an aerobic environment”. Thats what this is.
replied 2291d
For evolution you need something that can self replicate, mutate, & be under selection pressure. Self-Replicating RNA Enzymes suit those criteria.
Sk8eM dUb
replied 2291d
Just look at the long string of processes the chemists had to go through to make that RNA in the lab. Even then its just white noise and gets destroyed in the presence of oxygen.
replied 2288d
We’re also looking through the lens of survivorship bias. We dont know all the organisms that didn’t work out. It is possible there are even more simple self replicating molecules.
replied 2288d
& yes everything gets degraded over time. The question is what is the balance between self replicating & degrading? People degrade but not before self replicating.
Sk8eM dUb
replied 2287d
replied 2284d
wonderful animations. *yes people degrade constantly but not to the point they cannot self replicate (an assumption buried in previous mRNA enzyme posts)
Sk8eM dUb
replied 2283d
You don't get replication without that splitting machine, so that's something that has to jump out of your alphabet soup fully functional.
replied 2283d
true you dont get replication… in this organism. The RNA enzyme above can self replicate, & mutate. Minimum needed to evolve any function.
replied 2288d
Other groups work on how nucleotides & amino acids could be made in early earth conditions. side note: this was done in water in an open container at 42C so there was oxygen.